An eccentric schoolteacher takes her class on wondrous educational field trips with the help of a magical school bus.
Arnold's know-it-all cousin Janet drives the kids crazy when she joins Ms. Frizzle's class on a field trip and gets them lost in outer space!
Arnold's so excited he doesn't have to go on a field trip! But when he accidentally swallows his miniaturised class, he becomes the field trip!
Ralphie is crushed when a fever keeps him home from school the day he's scheduled to host a FNN (Frizzle News Network) television broadcast on health. With Tyne Daly as Ralphie’s mom.
Arnold and Keesha are in trouble when they forget to bring in their assignment on "two things that go together."
When Wanda's pet frog, Bella, jumps out an open window, Ms. Frizzle shrinks the bus into a mechanical frog and takes her now tiny class on a hop-along adventure.
It's "Accidental Science Project" day and the class has brought in marvelously rotten entries from the back of their refrigerators. With Ed Begley, Jr. as Larry Log-Away.